BRAF internal deletions and resistance to BRAF/MEK inhibitor therapy.

Johnson DB, Childress MA, Chalmers ZR, Frampton GM, Ali SM, Rubinstein SM, Fabrizio D, Ross JS, Balasubramanian S, Miller VA, Stephens PJ, Sosman JA, Lovly CM
Pigment Cell Melanoma Res. 2018 31 (3): 432-436

PMID: 29171936 · PMCID: PMC5889338 · DOI:10.1111/pcmr.12674

MeSH Terms (16)

Adult Amino Acid Substitution Base Sequence Drug Resistance, Neoplasm Female Humans Imidazoles MAP Kinase Signaling System Melanoma Mutation, Missense Oximes Protein Kinase Inhibitors Proto-Oncogene Proteins B-raf Pyridones Pyrimidinones Sequence Deletion

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