Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR
Nature. 2017 551 (7681): 464-471

PMID: 29160308 · PMCID: PMC5726555 · DOI:10.1038/nature24644

MeSH Terms (12)

Adenosine Deaminase Base Pairing Cell Line, Tumor CRISPR-Associated Proteins DNA DNA Cleavage Gene Editing Genome, Human HEK293 Cells Humans Models, Molecular Polymorphism, Single Nucleotide

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