Apical polarization and lumenogenesis: The apicosome sheds new light.

Romero-Morales AI, Ortolano NA, Gama V
J Cell Biol. 2017 216 (12): 3891-3893

PMID: 29138252 · PMCID: PMC5716292 · DOI:10.1083/jcb.201710028

Establishment of apico-basal polarity is critical for the lumenal epiblast-like morphogenesis of human pluripotent stem cells (hPSCs). In this issue, Taniguchi et al. (2017. https://doi.org/10.1083.jcb201704085) describe a structure called the apicosome, generated in single hPSCs, that allows them to self-organize and form the lumenal epiblast-like stage.

© 2017 Romero-Morales et al.

MeSH Terms (4)

Germ Layers Humans Morphogenesis Pluripotent Stem Cells

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