Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.

Bozadjieva N, Blandino-Rosano M, Chase J, Dai XQ, Cummings K, Gimeno J, Dean D, Powers AC, Gittes GK, Rüegg MA, Hall MN, MacDonald PE, Bernal-Mizrachi E
J Clin Invest. 2017 127 (12): 4379-4393

PMID: 29106387 · PMCID: PMC5707167 · DOI:10.1172/JCI90004

MeSH Terms (9)

Animals Glucagon Glucagon-Secreting Cells Hepatocyte Nuclear Factor 3-beta Mechanistic Target of Rapamycin Complex 1 Mice Mice, Knockout Regulatory-Associated Protein of mTOR Signal Transduction

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