MDM2 Antagonists Counteract Drug-Induced DNA Damage.

Vilgelm AE, Cobb P, Malikayil K, Flaherty D, Andrew Johnson C, Raman D, Saleh N, Higgins B, Vara BA, Johnston JN, Johnson DB, Kelley MC, Chen SC, Ayers GD, Richmond A
EBioMedicine. 2017 24: 43-55

PMID: 29030058 · PMCID: PMC5652019 · DOI:10.1016/j.ebiom.2017.09.016

MeSH Terms (20)

Animals Antineoplastic Combined Chemotherapy Protocols Azepines Cell Line, Tumor Cyclin-Dependent Kinase Inhibitor p21 DNA Damage DNA Replication HCT116 Cells Humans Imidazoles Melanoma Mice para-Aminobenzoates Piperazines Protein Binding Proto-Oncogene Proteins c-mdm2 Pyrimidines Pyrrolidines Tumor Suppressor Protein p53 Xenograft Model Antitumor Assays

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