Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin.

Erdogan B, Ao M, White LM, Means AL, Brewer BM, Yang L, Washington MK, Shi C, Franco OE, Weaver AM, Hayward SW, Li D, Webb DJ
J Cell Biol. 2017 216 (11): 3799-3816

PMID: 29021221 · PMCID: PMC5674895 · DOI:10.1083/jcb.201704053

MeSH Terms (20)

Cancer-Associated Fibroblasts Cell Communication Cell Line, Tumor Cell Movement Coculture Techniques Extracellular Matrix Fibronectins Humans Integrin alpha5beta1 Male Mechanotransduction, Cellular Neoplasm Invasiveness Nonmuscle Myosin Type IIA Prostatic Neoplasms Receptor, Platelet-Derived Growth Factor alpha RNA Interference Time Factors Transfection Tumor Cells, Cultured Tumor Microenvironment

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