MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation.

Lee KM, Giltnane JM, Balko JM, Schwarz LJ, Guerrero-Zotano AL, Hutchinson KE, Nixon MJ, Estrada MV, Sánchez V, Sanders ME, Lee T, Gómez H, Lluch A, Pérez-Fidalgo JA, Wolf MM, Andrejeva G, Rathmell JC, Fesik SW, Arteaga CL
Cell Metab. 2017 26 (4): 633-647.e7

PMID: 28978427 · PMCID: PMC5650077 · DOI:10.1016/j.cmet.2017.09.009

MeSH Terms (13)

Animals Cell Line, Tumor Drug Resistance, Neoplasm Female Humans Mice, Nude Mitochondria Myeloid Cell Leukemia Sequence 1 Protein Neoplastic Stem Cells Oxidative Phosphorylation Proto-Oncogene Proteins c-myc Reactive Oxygen Species Triple Negative Breast Neoplasms

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