Functional defects in TcdB toxin uptake identify CSPG4 receptor-binding determinants.

Gupta P, Zhang Z, Sugiman-Marangos SN, Tam J, Raman S, Julien JP, Kroh HK, Lacy DB, Murgolo N, Bekkari K, Therien AG, Hernandez LD, Melnyk RA
J Biol Chem. 2017 292 (42): 17290-17301

PMID: 28842504 · PMCID: PMC5655507 · DOI:10.1074/jbc.M117.806687

MeSH Terms (19)

Animals Antibodies, Monoclonal Antibodies, Neutralizing Bacterial Proteins Bacterial Toxins Broadly Neutralizing Antibodies Caco-2 Cells Chlorocebus aethiops CHO Cells Chondroitin Sulfate Proteoglycans Clostridioides difficile Cricetinae Cricetulus Glucosyltransferases HEK293 Cells Humans Membrane Proteins Protein Binding Protein Domains

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