Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles.

Pavlos R, McKinnon EJ, Ostrov DA, Peters B, Buus S, Koelle D, Chopra A, Schutte R, Rive C, Redwood A, Restrepo S, Bracey A, Kaever T, Myers P, Speers E, Malaker SA, Shabanowitz J, Jing Y, Gaudieri S, Hunt DF, Carrington M, Haas DW, Mallal S, Phillips EJ
Sci Rep. 2017 7 (1): 8653

PMID: 28819312 · PMCID: PMC5561238 · DOI:10.1038/s41598-017-08876-0

MeSH Terms (14)

Alleles Anti-HIV Agents Case-Control Studies Disease Susceptibility Drug Hypersensitivity Histocompatibility Antigens Class I Histocompatibility Antigens Class II Humans Nevirapine Odds Ratio Peptides Protein Binding Risk Assessment T-Lymphocytes

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