RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.

Dungrawala H, Bhat KP, Le Meur R, Chazin WJ, Ding X, Sharan SK, Wessel SR, Sathe AA, Zhao R, Cortez D
Mol Cell. 2017 67 (3): 374-386.e5

PMID: 28735897 · PMCID: PMC5548441 · DOI:10.1016/j.molcel.2017.06.023

MeSH Terms (23)

A549 Cells Animals BRCA2 Protein CRISPR-Cas Systems DNA, Neoplasm DNA Breaks, Double-Stranded DNA Repair Dose-Response Relationship, Drug Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic Genomic Instability HEK293 Cells Humans Mice Models, Molecular Mutation Neoplasms Poly(ADP-ribose) Polymerase Inhibitors Protein Binding Rad51 Recombinase Replication Origin RNA Interference Transfection

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