Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.

Shimada T, Murayama N, Kakimoto K, Takenaka S, Lim YR, Yeom S, Kim D, Yamazaki H, Guengerich FP, Komori M
Xenobiotica. 2018 48 (6): 565-575

PMID: 28648140 · PMCID: PMC5780263 · DOI:10.1080/00498254.2017.1347306

MeSH Terms (8)

Alleles Aryl Hydrocarbon Hydroxylases Biocatalysis Cytochrome P-450 CYP1B1 Humans Molecular Docking Simulation Oxidation-Reduction Pyrenes

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