Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2 Dravet syndrome mice.

Huang X, Zhou C, Tian M, Kang JQ, Shen W, Verdier K, Pimenta A, MacDonald RL
Epilepsia. 2017 58 (8): 1451-1461

PMID: 28586508 · PMCID: PMC5554098 · DOI:10.1111/epi.13810

MeSH Terms (21)

Action Potentials Animals Convulsants Electric Stimulation Epilepsies, Myoclonic Humans Inhibitory Postsynaptic Potentials In Vitro Techniques Male Mice Mice, Inbred C57BL Mice, Transgenic Mutation Neural Pathways Patch-Clamp Techniques Pentylenetetrazole Protein Subunits Pyramidal Cells Receptors, GABA-A Somatosensory Cortex Thalamus

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