Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapy.

Kasper S, Reis H, Ziegler S, Nothdurft S, Mueller A, Goetz M, Wiesweg M, Phasue J, Ting S, Wieczorek S, Even A, Worm K, Pogorzelski M, Breitenbuecher S, Meiler J, Paul A, Trarbach T, Schmid KW, Breitenbuecher F, Schuler M
Oncotarget. 2017 8 (28): 45898-45917

PMID: 28507280 · PMCID: PMC5542236 · DOI:10.18632/oncotarget.17438

MeSH Terms (17)

Antineoplastic Agents, Immunological Apoptosis Biomarkers Cell Line, Tumor Colorectal Neoplasms Drug Resistance, Neoplasm ErbB Receptors Exons Genes, ras Humans Mitogen-Activated Protein Kinases Mutation Odds Ratio Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-bcl-2 Signal Transduction

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