Regional differences in rat brain displayed by fast MRI with superparamagnetic contrast agents.

Majumdar S, Zoghbi SS, Gore JC
Magn Reson Imaging. 1988 6 (6): 611-5

PMID: 2850431 · DOI:10.1016/0730-725x(88)90082-3

Gradient echo images of coronal sections through the brains of normal rats have been recorded at 2.0 T both before and at various times after intravenous bolus administrations of a superparamagnetic iron oxide suspension. The decrease in NMR signal due to the transit of the contrast agent has been quantified as a function of time. The image immediately following the injection can be subtracted from that pre-contrast to reveal regional differences related to blood flow.

MeSH Terms (14)

Animals Blood Volume Brain Cerebrovascular Circulation Contrast Media Electron Spin Resonance Spectroscopy Ferric Compounds Magnetic Resonance Imaging Male Radionuclide Imaging Rats Rats, Inbred Strains Sodium Pertechnetate Tc 99m Subtraction Technique

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