Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.

Karnes JH, Bastarache L, Shaffer CM, Gaudieri S, Xu Y, Glazer AM, Mosley JD, Zhao S, Raychaudhuri S, Mallal S, Ye Z, Mayer JG, Brilliant MH, Hebbring SJ, Roden DM, Phillips EJ, Denny JC
Sci Transl Med. 2017 9 (389)

PMID: 28490672 · PMCID: PMC5563969 · DOI:10.1126/scitranslmed.aai8708

MeSH Terms (8)

Alleles Diabetes Mellitus, Type 1 Genetic Predisposition to Disease Genome-Wide Association Study Histocompatibility Antigens Class II HLA-DQ beta-Chains Humans Polymorphism, Single Nucleotide

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