Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs.

Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F
Stem Cell Reports. 2017 8 (5): 1202-1213

PMID: 28457885 · PMCID: PMC5425682 · DOI:10.1016/j.stemcr.2017.03.022

MeSH Terms (15)

Animals Arthritis Cartilage Cells, Cultured CRISPR-Cas Systems Feedback, Physiological Gene Editing Immunologic Factors Induced Pluripotent Stem Cells Interleukin-1 Mice Mice, Inbred C57BL Regeneration Stem Cell Transplantation Tumor Necrosis Factor-alpha

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