Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.

Zhou T, Doria-Rose NA, Cheng C, Stewart-Jones GBE, Chuang GY, Chambers M, Druz A, Geng H, McKee K, Kwon YD, O'Dell S, Sastry M, Schmidt SD, Xu K, Chen L, Chen RE, Louder MK, Pancera M, Wanninger TG, Zhang B, Zheng A, Farney SK, Foulds KE, Georgiev IS, Joyce MG, Lemmin T, Narpala S, Rawi R, Soto C, Todd JP, Shen CH, Tsybovsky Y, Yang Y, Zhao P, Haynes BF, Stamatatos L, Tiemeyer M, Wells L, Scorpio DG, Shapiro L, McDermott AB, Mascola JR, Kwong PD
Cell Rep. 2017 19 (4): 719-732

PMID: 28445724 · PMCID: PMC5538809 · DOI:10.1016/j.celrep.2017.04.013

MeSH Terms (18)

Animals Antibodies, Neutralizing Antibody Specificity Binding Sites CD4 Antigens Crystallography, X-Ray env Gene Products, Human Immunodeficiency Virus Epitopes Glycosylation Guinea Pigs HIV-1 HIV Antibodies Humans Immunization Macaca mulatta Molecular Dynamics Simulation Polysaccharides Protein Structure, Quaternary

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