SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer.

Ichihara E, Westover D, Meador CB, Yan Y, Bauer JA, Lu P, Ye F, Kulick A, de Stanchina E, McEwen R, Ladanyi M, Cross D, Pao W, Lovly CM
Cancer Res. 2017 77 (11): 2990-3000

PMID: 28416483 · PMCID: PMC5467531 · DOI:10.1158/0008-5472.CAN-16-2300

MeSH Terms (17)

Acrylamides Aniline Compounds Animals Antineoplastic Agents Drug Resistance, Neoplasm ErbB Receptors Female Focal Adhesion Protein-Tyrosine Kinases Humans Lung Neoplasms Mice Mice, Nude Mutation Piperazines Signal Transduction src-Family Kinases Transfection

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