SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.

Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD
Cell Metab. 2017 25 (4): 838-855.e15

PMID: 28380376 · PMCID: PMC5444661 · DOI:10.1016/j.cmet.2017.03.003

MeSH Terms (20)

Amidohydrolases Amino Acid Sequence Animals Carbon-Carbon Ligases Glucose HEK293 Cells Homeostasis Humans Insulin Insulin Resistance Insulin Secretion Leucine Lysine Metabolic Flux Analysis Mice, Inbred C57BL Mice, Knockout Mitochondrial Proteins Models, Molecular Phylogeny Sirtuins

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