Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer.

Li C, Singh B, Graves-Deal R, Ma H, Starchenko A, Fry WH, Lu Y, Wang Y, Bogatcheva G, Khan MP, Milne GL, Zhao S, Ayers GD, Li N, Hu H, Washington MK, Yeatman TJ, McDonald OG, Liu Q, Coffey RJ
Proc Natl Acad Sci U S A. 2017 114 (14): E2852-E2861

PMID: 28320945 · PMCID: PMC5389279 · DOI:10.1073/pnas.1618297114

MeSH Terms (22)

Animals Antineoplastic Agents, Immunological Cell Culture Techniques Cell Line, Tumor Cetuximab Colorectal Neoplasms Crizotinib Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic Humans Hydroxyprostaglandin Dehydrogenases Mice Phosphorylation Protein-Serine-Threonine Kinases Proto-Oncogene Proteins c-akt Pyrazoles Pyridines Receptor, Transforming Growth Factor-beta Type II Receptors, Transforming Growth Factor beta Tissue Array Analysis Versicans Xenograft Model Antitumor Assays

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