Heart Failure Incidence and Mortality in the Southern Community Cohort Study.

Akwo EA, Kabagambe EK, Wang TJ, Harrell FE, Blot WJ, Mumma M, Gupta DK, Lipworth L
Circ Heart Fail. 2017 10 (3)

PMID: 28255010 · PMCID: PMC5365148 · DOI:10.1161/CIRCHEARTFAILURE.116.003553

BACKGROUND - There is a paucity of data on heart failure (HF) incidence among low-income and minority populations. Our objective was to investigate HF incidence and post-HF survival by race and sex among low-income adults in the southeastern United States.

METHODS AND RESULTS - Participants were 27 078 white and black men and women enrolled during 2002 to 2009 in the SCCS (Southern Community Cohort Study) who had no history of HF and were receiving Centers for Medicare and Medicaid Services. Incident HF diagnoses through December 31, 2010 were ascertained using 9th Revision codes 428.x via linkage with Centers for Medicare and Medicaid Services research files. Most participants were black (68.8%), women (62.6%), and earned <$15 000/y (69.7%); mean age was 55.5 (10.4) years. Risk factors for HF were common: hypertension (62.5%), diabetes mellitus (26.5%), myocardial infarction (8.6%), and obesity (44.8%). Over a median follow-up of 5.2 years, 4341 participants were diagnosed with HF. The age-standardized incidence rates were 34.8, 37.3, 34.9, and 35.6 /1000 person-years in white women, white men, black men, and black women, respectively, remarkably higher than previously reported. Among HF cases, 952 deaths occurred over a median follow-up of 2.3 years. Men had lower survival; hazard ratios and 95% confidence intervals were 1.63 (1.27-2.08), 1.38 (1.11-1.72), and 0.90 (0.73-1.12) for white men, black men, and black women compared with white women.

CONCLUSIONS - In this low-income population, HF incidence was higher for all race-sex groups than previously reported in other cohorts. The SCCS is a unique resource to investigate determinants of HF risk in a segment of the population underrepresented in other existing cohorts.

© 2017 American Heart Association, Inc.

MeSH Terms (20)

Adult African Americans Aged Comorbidity European Continental Ancestry Group Female Heart Failure Humans Incidence Male Middle Aged Poverty Prognosis Proportional Hazards Models Prospective Studies Risk Assessment Risk Factors Sex Distribution Southeastern United States Time Factors

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