The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.

O'Brien E, Holt ME, Thompson MK, Salay LE, Ehlinger AC, Chazin WJ, Barton JK
Science. 2017 355 (6327)

PMID: 28232525 · PMCID: PMC5338353 · DOI:10.1126/science.aag1789

MeSH Terms (12)

Biological Transport DNA DNA Primase DNA Replication Electrolysis Humans Iron-Sulfur Proteins Mutation Oxidation-Reduction Polymerization Protein Binding Protein Domains

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