High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC
Sci Transl Med. 2017 9 (377)

PMID: 28202772 · PMCID: PMC5409837 · DOI:10.1126/scitranslmed.aaf2584

MeSH Terms (15)

Biomarkers Cardiotoxicity Fibroblasts High-Throughput Screening Assays Humans Induced Pluripotent Stem Cells Insulin Insulin-Like Growth Factor I Models, Biological Myocytes, Cardiac Phosphorylation Protein Kinase Inhibitors Sarcomeres Signal Transduction Vascular Endothelial Growth Factor Receptor-2

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