Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors.

Polosukhina D, Love HD, Correa H, Su Z, Dahlman KB, Pao W, Moses HL, Arteaga CL, Lovvorn HN, Zent R, Clark PE
Mol Oncol. 2017 11 (4): 405-421

PMID: 28188683 · PMCID: PMC5378659 · DOI:10.1002/1878-0261.12044

MeSH Terms (18)

Animals Base Sequence beta Catenin Cell Movement Cell Proliferation Cell Transformation, Neoplastic Disease Progression Enzyme Activation Humans Immunohistochemistry Kidney Neoplasms Mice, Inbred C57BL Mutation Neoplasm Metastasis Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins p21(ras) Wilms Tumor

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