Integrated analysis of genetic variation and gene expression reveals novel variant for increased warfarin dose requirement in African Americans.

Hernandez W, Gamazon ER, Aquino-Michaels K, Smithberger E, O'Brien TJ, Harralson AF, Tuck M, Barbour A, Cavallari LH, Perera MA
J Thromb Haemost. 2017 15 (4): 735-743

PMID: 28135054 · PMCID: PMC5862636 · DOI:10.1111/jth.13639

MeSH Terms (23)

Adult African Americans Aged Algorithms Calcium-Binding Proteins Cohort Studies Cytochrome P-450 CYP2C9 Female Gene Expression Profiling Gene Expression Regulation Genetic Variation Genotype Humans Linkage Disequilibrium Liver Male Middle Aged Pharmacogenetics Precision Medicine Quantitative Trait Loci Thromboembolism Vitamin K Epoxide Reductases Warfarin

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