Key Survival Factor, Mcl-1, Correlates with Sensitivity to Combined Bcl-2/Bcl-xL Blockade.

Williams MM, Lee L, Hicks DJ, Joly MM, Elion D, Rahman B, McKernan C, Sanchez V, Balko JM, Stricker T, Estrada MV, Cook RS
Mol Cancer Res. 2017 15 (3): 259-268

PMID: 28039357 · PMCID: PMC5334148 · DOI:10.1158/1541-7786.MCR-16-0280-T

MeSH Terms (15)

Aniline Compounds Antineoplastic Agents bcl-X Protein Breast Neoplasms Cell Line, Tumor Cell Survival Estrogen Receptor alpha Female Humans MCF-7 Cells Myeloid Cell Leukemia Sequence 1 Protein Neoplasms Proto-Oncogene Proteins c-bcl-2 RNA, Messenger Sulfonamides

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