Matrix stiffening promotes a tumor vasculature phenotype.

Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA
Proc Natl Acad Sci U S A. 2017 114 (3): 492-497

PMID: 28034921 · PMCID: PMC5255592 · DOI:10.1073/pnas.1613855114

MeSH Terms (19)

Animals Biomechanical Phenomena Cattle Cells, Cultured Chick Embryo Collagen Extracellular Matrix Female Humans Human Umbilical Vein Endothelial Cells Mammary Neoplasms, Experimental Matrix Metalloproteinases Mice Microvessels Neoplasm Invasiveness Neovascularization, Pathologic Phenotype Tumor Microenvironment Vascular Stiffness

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