F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials.

Wang Y, Ayres KL, Goldman DA, Dickler MN, Bardia A, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC, Mahmood U, Ulaner GA
Clin Cancer Res. 2017 23 (12): 3053-3060

PMID: 28011460 · PMCID: PMC5474190 · DOI:10.1158/1078-0432.CCR-16-2197

MeSH Terms (18)

Adult Aged Biomarkers, Pharmacological Breast Neoplasms Cinnamates Dose-Response Relationship, Drug Estradiol Estrogen Receptor alpha Female Fulvestrant Humans Indazoles Middle Aged Molecular Imaging Molecular Targeted Therapy Positron Emission Tomography Computed Tomography Receptors, Estrogen Tamoxifen

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