PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses.

Sai J, Owens P, Novitskiy SV, Hawkins OE, Vilgelm AE, Yang J, Sobolik T, Lavender N, Johnson AC, McClain C, Ayers GD, Kelley MC, Sanders M, Mayer IA, Moses HL, Boothby M, Richmond A
Clin Cancer Res. 2017 23 (13): 3371-3384

PMID: 28003307 · PMCID: PMC5479746 · DOI:10.1158/1078-0432.CCR-16-2142

MeSH Terms (18)

Aminopyridines Animals Cell Line, Tumor Cell Proliferation Class Ib Phosphatidylinositol 3-Kinase Female Humans Immunity, Cellular Mammary Neoplasms, Animal Mice Morpholines Neoplasm Metastasis Phosphoinositide-3 Kinase Inhibitors Programmed Cell Death 1 Receptor Protein Kinase Inhibitors Signal Transduction Triple Negative Breast Neoplasms Xenograft Model Antitumor Assays

Connections (6)

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