Diverse Effects on M Signaling and Adverse Effect Liability within a Series of M Ago-PAMs.

Rook JM, Abe M, Cho HP, Nance KD, Luscombe VB, Adams JJ, Dickerson JW, Remke DH, Garcia-Barrantes PM, Engers DW, Engers JL, Chang S, Foster JJ, Blobaum AL, Niswender CM, Jones CK, Conn PJ, Lindsley CW
ACS Chem Neurosci. 2017 8 (4): 866-883

PMID: 28001356 · PMCID: PMC5460155 · DOI:10.1021/acschemneuro.6b00429

MeSH Terms (9)

Allosteric Regulation Animals Drug Discovery Humans Mice Muscarinic Agonists Rats Receptor, Muscarinic M1 Structure-Activity Relationship

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