Electrophilic Modification of PKM2 by 4-Hydroxynonenal and 4-Oxononenal Results in Protein Cross-Linking and Kinase Inhibition.

Camarillo JM, Ullery JC, Rose KL, Marnett LJ
Chem Res Toxicol. 2017 30 (2): 635-641

PMID: 27978618 · PMCID: PMC5318235 · DOI:10.1021/acs.chemrestox.6b00374

MeSH Terms (9)

Aldehydes Cell Line, Tumor Chromatography, Liquid Click Chemistry Enzyme Inhibitors Humans Ketones Pyruvate Kinase Tandem Mass Spectrometry

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