Novel Small Molecule JP-153 Targets the Src-FAK-Paxillin Signaling Complex to Inhibit VEGF-Induced Retinal Angiogenesis.

Toutounchian JJ, Pagadala J, Miller DD, Baudry J, Park F, Chaum E, Morales-Tirado , Yates CR
Mol Pharmacol. 2017 91 (1): 1-13

PMID: 27913654 · DOI:10.1124/mol.116.105031

MeSH Terms (17)

Animals Benzoxazines Cell Movement Cell Proliferation Disease Models, Animal Endothelial Cells Focal Adhesion Protein-Tyrosine Kinases Humans Mice, Inbred C57BL Models, Biological Oxygen Paxillin Retinal Neovascularization Signal Transduction Small Molecule Libraries src-Family Kinases Vascular Endothelial Growth Factor A

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