A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y R Antagonists.

Burkert K, Zellmann T, Meier R, Kaiser A, Stichel J, Meiler J, Mittapalli GK, Roberts E, Beck-Sickinger AG
ChemMedChem. 2017 12 (1): 75-85

PMID: 27874262 · DOI:10.1002/cmdc.201600433

MeSH Terms (15)

Animals Arginine Benzazepines Binding Sites Cells, Cultured Chlorocebus aethiops COS Cells Dose-Response Relationship, Drug HEK293 Cells Humans Hydrophobic and Hydrophilic Interactions Molecular Docking Simulation Molecular Structure Receptors, Neuropeptide Y Structure-Activity Relationship

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