Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, Wu F, Doria-Rose NA, Zhang B, McKee K, O'Dell S, Chuang GY, Druz A, Georgiev IS, Schramm CA, Zheng A, Joyce MG, Asokan M, Ransier A, Darko S, Migueles SA, Bailer RT, Louder MK, Alam SM, Parks R, Kelsoe G, Von Holle T, Haynes BF, Douek DC, Hirsch V, Seaman MS, Shapiro L, Mascola JR, Kwong PD, Connors M
Immunity. 2016 45 (5): 1108-1121

PMID: 27851912 · PMCID: PMC5770152 · DOI:10.1016/j.immuni.2016.10.027

MeSH Terms (10)

Antibodies, Neutralizing Antibody Specificity Binding Sites, Antibody CD4-Positive T-Lymphocytes Cell Separation HIV-1 HIV Antibodies HIV Envelope Protein gp120 HIV Infections Humans

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