Identification of the minimum PAR4 inhibitor pharmacophore and optimization of a series of 2-methoxy-6-arylimidazo[2,1-b][1,3,4]thiadiazoles.

Temple KJ, Duvernay MT, Maeng JG, Blobaum AL, Stauffer SR, Hamm HE, Lindsley CW
Bioorg Med Chem Lett. 2016 26 (22): 5481-5486

PMID: 27777004 · PMCID: PMC5340293 · DOI:10.1016/j.bmcl.2016.10.020

MeSH Terms (7)

Blood Platelets Humans Platelet Aggregation Platelet Aggregation Inhibitors Receptors, Thrombin Thiadiazoles Thrombin

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