The Pursuit of Noninvasive Diagnosis of Lung Cancer.

Atwater T, Cook CM, Massion PP
Semin Respir Crit Care Med. 2016 37 (5): 670-680

PMID: 27732989 · PMCID: PMC5317274 · DOI:10.1055/s-0036-1592314

The noninvasive diagnosis of lung cancer remains a formidable challenge. Although tissue diagnosis will remain the gold standard for the foreseeable future, questions pertaining to the risks and costs associated with invasive diagnostic procedures are of prime relevance. This review addresses new modalities for improving the noninvasive evaluation of suspicious lung nodules. Ultimately, the goal is to translate early diagnosis into early treatment. We discuss how biomarkers could assist in distinguishing benign from malignant nodules and aggressive from indolent tumors. The field of biomarkers is rapidly expanding and progressing, and efforts are well underway to apply molecular diagnostics to address the shortcomings of current lung cancer diagnostic tools.

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

MeSH Terms (5)

Biomarkers, Tumor Humans Lung Neoplasms Multiple Pulmonary Nodules Solitary Pulmonary Nodule

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