Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma.

McFadden DG, Politi K, Bhutkar A, Chen FK, Song X, Pirun M, Santiago PM, Kim-Kiselak C, Platt JT, Lee E, Hodges E, Rosebrock AP, Bronson RT, Socci ND, Hannon GJ, Jacks T, Varmus H
Proc Natl Acad Sci U S A. 2016 113 (42): E6409-E6417

PMID: 27702896 · PMCID: PMC5081629 · DOI:10.1073/pnas.1613601113

MeSH Terms (21)

Adenocarcinoma Adenocarcinoma of Lung Animals Carcinogens Cell Transformation, Neoplastic Disease Models, Animal DNA Copy Number Variations DNA Mutational Analysis ErbB Receptors Gene Dosage Genes, myc Genes, ras Genome-Wide Association Study Lung Neoplasms Mice Mice, Transgenic Mutation Point Mutation Proto-Oncogene Mas ROC Curve Whole Exome Sequencing

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