Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.

Harlow ML, Maloney N, Roland J, Guillen Navarro MJ, Easton MK, Kitchen-Goosen SM, Boguslawski EA, Madaj ZB, Johnson BK, Bowman MJ, D'Incalci M, Winn ME, Turner L, Hostetter G, Galmarini CM, Aviles PM, Grohar PJ
Cancer Res. 2016 76 (22): 6657-6668

PMID: 27697767 · PMCID: PMC5567825 · DOI:10.1158/0008-5472.CAN-16-0568

MeSH Terms (13)

Animals Camptothecin Cell Line, Tumor Female Humans Irinotecan Mice Mice, Nude Oncogene Proteins Oncogene Proteins, Fusion Proto-Oncogene Protein c-fli-1 RNA-Binding Protein EWS Sarcoma, Ewing

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