Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release.

Foster DJ, Wilson JM, Remke DH, Mahmood MS, Uddin MJ, Wess J, Patel S, Marnett LJ, Niswender CM, Jones CK, Xiang Z, Lindsley CW, Rook JM, Conn PJ
Neuron. 2016 91 (6): 1244-1252

PMID: 27618677 · PMCID: PMC5033724 · DOI:10.1016/j.neuron.2016.08.017

MeSH Terms (14)

Allosteric Regulation Animals Antipsychotic Agents Corpus Striatum Dopamine Lipoprotein Lipase Mice, Knockout Muscarinic Agonists Oxotremorine Prepulse Inhibition Pyridazines Receptor, Cannabinoid, CB2 Receptor, Muscarinic M4 Thiophenes

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