Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M PAM VU6004256.

Grannan MD, Mielnik CA, Moran SP, Gould RW, Ball J, Lu Z, Bubser M, Ramsey AJ, Abe M, Cho HP, Nance KD, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW, Jones CK
ACS Chem Neurosci. 2016 7 (12): 1706-1716

PMID: 27617634 · PMCID: PMC5231396 · DOI:10.1021/acschemneuro.6b00230

MeSH Terms (23)

Action Potentials Animals Cholinergic Agents Cognition Disorders Conditioning, Psychological Disease Models, Animal Drug Evaluation, Preclinical Fear Gene Knockdown Techniques Heterocyclic Compounds, 4 or More Rings Long-Term Synaptic Depression Male Mice, 129 Strain Mice, Inbred C57BL Mice, Transgenic Motor Activity Nerve Tissue Proteins Nootropic Agents Prefrontal Cortex Pyramidal Cells Receptors, N-Methyl-D-Aspartate Recognition, Psychology Tissue Culture Techniques

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