Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.

Tian M, Cheng C, Chen X, Duan H, Cheng HL, Dao M, Sheng Z, Kimble M, Wang L, Lin S, Schmidt SD, Du Z, Joyce MG, Chen Y, DeKosky BJ, Chen Y, Normandin E, Cantor E, Chen RE, Doria-Rose NA, Zhang Y, Shi W, Kong WP, Choe M, Henry AR, Laboune F, Georgiev IS, Huang PY, Jain S, McGuire AT, Georgeson E, Menis S, Douek DC, Schief WR, Stamatatos L, Kwong PD, Shapiro L, Haynes BF, Mascola JR, Alt FW
Cell. 2016 166 (6): 1471-1484.e18

PMID: 27610571 · PMCID: PMC5103708 · DOI:10.1016/j.cell.2016.07.029

MeSH Terms (17)

Animals Antibodies, Monoclonal Antibodies, Neutralizing B-Lymphocytes Broadly Neutralizing Antibodies Cell Line Disease Models, Animal Gene Expression Regulation HIV-1 HIV Antibodies Immunization Immunoglobulin Heavy Chains Inhibitory Concentration 50 Mice Precursor Cells, B-Lymphoid Sequence Deletion T-Lymphocytes

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