Development of a RSK Inhibitor as a Novel Therapy for Triple-Negative Breast Cancer.

Ludwik KA, Campbell JP, Li M, Li Y, Sandusky ZM, Pasic L, Sowder ME, Brenin DR, Pietenpol JA, O'Doherty GA, Lannigan DA
Mol Cancer Ther. 2016 15 (11): 2598-2608

PMID: 27528706 · PMCID: PMC5807013 · DOI:10.1158/1535-7163.MCT-16-0106

MeSH Terms (22)

Animals Antineoplastic Agents Benzopyrans Cell Line, Tumor Cell Movement Cell Proliferation Cell Survival Disease Models, Animal Dose-Response Relationship, Drug Enzyme Activation Female Gene Silencing Humans Mice Monosaccharides Neoplasm Metastasis Protein Kinase Inhibitors Proto-Oncogene Proteins c-akt Ribosomal Protein S6 Kinases, 90-kDa Triple Negative Breast Neoplasms Tumor Burden Xenograft Model Antitumor Assays

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