Assessment of Protein Binding of 5-Hydroxythalidomide Bioactivated in Humanized Mice with Human P450 3A-Chromosome or Hepatocytes by Two-Dimensional Electrophoresis/Accelerator Mass Spectrometry.

Yamazaki H, Suemizu H, Kazuki Y, Oofusa K, Kuribayashi S, Shimizu M, Ninomiya S, Horie T, Shibata N, Guengerich FP
Chem Res Toxicol. 2016 29 (8): 1279-81

PMID: 27464947 · PMCID: PMC5282975 · DOI:10.1021/acs.chemrestox.6b00210

MeSH Terms (9)

Animals Cytochrome P-450 Enzyme System Electrophoresis, Gel, Two-Dimensional Hepatocytes Humans Mass Spectrometry Mice Protein Binding Thalidomide

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