Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice.

Ade KK, Wan Y, Hamann HC, O'Hare JK, Guo W, Quian A, Kumar S, Bhagat S, Rodriguiz RM, Wetsel WC, Conn PJ, Dzirasa K, Huber KM, Calakos N
Biol Psychiatry. 2016 80 (7): 522-33

PMID: 27436084 · PMCID: PMC5536332 · DOI:10.1016/j.biopsych.2016.04.023

MeSH Terms (17)

Animals Behavior, Animal Corpus Striatum Excitatory Amino Acid Agonists Excitatory Amino Acid Antagonists Glycine Grooming Mice Mice, Knockout Mice, Transgenic Nerve Tissue Proteins Niacinamide Obsessive-Compulsive Disorder Pyridines Receptor, Metabotropic Glutamate 5 Signal Transduction Thiazoles

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