Cytochrome P450 metabolism of the post-lanosterol intermediates explains enigmas of cholesterol synthesis.

Ačimovič J, Goyal S, Košir R, Goličnik M, Perše M, Belič A, Urlep Ž, Guengerich FP, Rozman D
Sci Rep. 2016 6: 28462

PMID: 27334049 · PMCID: PMC4917857 · DOI:10.1038/srep28462

MeSH Terms (16)

Animals Cholesterol Cyclic AMP Response Element Modulator Cytochrome P-450 Enzyme System Gas Chromatography-Mass Spectrometry Humans Lanosterol Male Mice Mice, Knockout Models, Theoretical Oxidation-Reduction Rats Recombinant Proteins Sterols Testis

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