NF-κB and androgen receptor variant 7 induce expression of SRD5A isoforms and confer 5ARI resistance.

Austin DC, Strand DW, Love HL, Franco OE, Grabowska MM, Miller NL, Hameed O, Clark PE, Matusik RJ, Jin RJ, Hayward SW
Prostate. 2016 76 (11): 1004-18

PMID: 27197599 · PMCID: PMC4912960 · DOI:10.1002/pros.23195

MeSH Terms (23)

3-Oxo-5-alpha-Steroid 4-Dehydrogenase 5-alpha Reductase Inhibitors Animals Apoptosis Drug Resistance Gene Expression Gene Knockdown Techniques Humans Isoenzymes Lower Urinary Tract Symptoms Male Membrane Proteins Mice Mice, Nude NF-kappa B Orchiectomy Prostate Prostatic Hyperplasia Prostatic Neoplasms, Castration-Resistant Receptors, Androgen Testosterone Treatment Failure Up-Regulation

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