The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis.

Astudillo L, Da Silva TG, Wang Z, Han X, Jin K, VanWye J, Zhu X, Weaver K, Oashi T, Lopes PE, Orton D, Neitzel LR, Lee E, Landgraf R, Robbins DJ, MacKerell AD, Capobianco AJ
Cancer Res. 2016 76 (12): 3593-603

PMID: 27197169 · PMCID: PMC4911243 · DOI:10.1158/0008-5472.CAN-16-0061

MeSH Terms (12)

Animals Cell Line, Tumor DNA-Binding Proteins Humans Mice Neoplasms Receptors, Notch Somites Thiazolidines Transcriptional Activation Transcription Factors Zebrafish

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