Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.

Morrison Joly M, Hicks DJ, Jones B, Sanchez V, Estrada MV, Young C, Williams M, Rexer BN, Sarbassov dos D, Muller WJ, Brantley-Sieders D, Cook RS
Cancer Res. 2016 76 (16): 4752-64

PMID: 27197158 · PMCID: PMC5758362 · DOI:10.1158/0008-5472.CAN-15-3393

MeSH Terms (20)

Animals Blotting, Western Breast Neoplasms Carrier Proteins Disease Progression Drug Resistance, Neoplasm Female Heterografts Humans Kaplan-Meier Estimate Mechanistic Target of Rapamycin Complex 2 Mice Mice, Inbred BALB C Mice, Nude Multiprotein Complexes Rapamycin-Insensitive Companion of mTOR Protein Receptor, ErbB-2 Signal Transduction Tissue Array Analysis TOR Serine-Threonine Kinases

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