Collybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activity.

Gupta A, Gomes I, Bobeck EN, Fakira AK, Massaro NP, Sharma I, Cavé A, Hamm HE, Parello J, Devi LA
Proc Natl Acad Sci U S A. 2016 113 (21): 6041-6

PMID: 27162327 · PMCID: PMC4889365 · DOI:10.1073/pnas.1521825113

MeSH Terms (11)

Agaricales Animals Antipruritics Diterpenes, Clerodane HEK293 Cells Humans MAP Kinase Signaling System Mice Mice, Knockout Receptors, Opioid, kappa Second Messenger Systems

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