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Novel PAMs Targeting NMDAR GluN2A Subunit.

Xiang Z, Conn PJ
Neuron. 2016 89 (5): 884-6

PMID: 26938436 · PMCID: PMC4793964 · DOI:10.1016/j.neuron.2016.02.025

In this issue of Neuron, Hackos et al. (2016) report the discovery of novel positive allosteric modulators that are highly selective for GluN2A-containing NMDA receptors. This novel class of PAMs shows distinct effects on synaptic plasticity.

Copyright © 2016 Elsevier Inc. All rights reserved.

MeSH Terms (6)

Animals Humans Models, Molecular Nerve Net Neurons Receptors, N-Methyl-D-Aspartate

Connections (1)

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